Daniel Wilson's Blog

Research in Population Genomics

Monday, 5 January 2026

New paper: Identifying direct risk factors for COVID-19 hospitalization in UK Biobank using Doublethink

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This week sees publication of our new paper  Identifying direct risk factors in UK Biobank via simultaneous Bayesian-frequentist model-avera...
Tuesday, 14 October 2025

New paper: Machine learning and statistical inference in microbial population genomics

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We have published a new review article in Genome Biology contrasting machine learning and statistics in microbial genomics. This is joint w...
Monday, 12 May 2025

Doublethink: simultaneous Bayesian-frequentist model-averaged hypothesis testing

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Helen Fryer, Nick Arning and I have posted our new preprint to arxiv . This is the first version of the paper that we have submitted for pee...
Wednesday, 2 April 2025

Machine Learning versus Statistical Inference in Microbial Genomics

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My talk given today at the 2025 Microbiology Society Conference in Liverpool: Abstract The advent of vast genomic datasets has transform...
Friday, 15 November 2024

What Google AI thinks about the harmonic mean p-value method.

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Thanks to Jeff Chen who asked Google NotebookLM to produce this radio-style audio description of the harmonic mean p -value paper: hmp-googl...
Monday, 29 July 2024

Doublethink methods paper

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Today we release the first full draft of the Doublethink methods paper . This is an evolution of what was originally conceived as the supple...
Tuesday, 23 January 2024

Festival of Genomics 2024

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I will be talking at the Festival of Genomics on Wednesday 24 January about Identifying virulence and antimicrobial resistance genes in bact...
Wednesday, 3 January 2024

Introducing Doublethink: joint Bayesian-frequentist model-averaged hypothesis testing

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This week Nick Arning, Helen Fryer and I released two related preprints describing a new method called Doublethink, and its application to i...
Wednesday, 28 September 2022

Rewley House Lecture: Role of data science in the pandemic

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This year I was invited to give the Rewley House Lecture , a multidisciplinary research talk open to all, at the Department for Continuing E...
Thursday, 25 August 2022

Identifying resistance genes in tuberculosis

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Newly published in PLOS Biology is our work identifying genes that confer resistance to common and last-resort antibiotics in bacteria tha...
Wednesday, 23 February 2022

Seeking Postdoc in Statistical Genetics and Infectious Disease

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I am seeking a senior postdoc in Statistical Genetics and Infectious Disease to join my research group at the Big Data Institute, Universit...

Announcing the Oxford Statistical Genomics Summer School 2022

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Join us at St Hilda's College Oxford, overlooking the River Cherwell and Christ Church Meadow, for an immersive week-long residential po...
Wednesday, 26 January 2022

Postdoctoral and Ph.D. positions in the group

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If you are interested in joining the group, please contact me ( details here ) with a brief explanation and a copy of an up-to-date CV.
Tuesday, 25 January 2022

Announcing ProbGen22 in Oxford 28-30 March

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The organizing committee is pleased to announce the 7th Probabilistic Modeling in Genomics Conference (ProbGen22) to be held at the Blavatni...
Tuesday, 7 December 2021

Two new positions: Senior Statistical Geneticist and Bioinformatician

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Two new positions are available in my Infectious Disease Genomics group at the Big Data Institute, University of Oxford. A Senior Postdocto...

New paper: Machine learning to predict the source of campylobacteriosis using whole genome data

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This study, published in October in PLOS Genetics , brings together machine learning, large bacterial isolate collections and whole genome s...

New paper: Antimicrobial resistance determinants are associated with Staphylococcus aureus bacteraemia and adaptation to the healthcare environment

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Staphylococcus aureus  is a leading cause of infectious disease deaths in all countries, with bloodstream infection leading to sepsis a majo...

New paper: Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis

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In this paper, published in October in PLOS Pathogens , we discovered a novel genetic association between life-threatening invasive meningoc...
Tuesday, 13 April 2021

New positions: Data Scientist in Public Health Epidemiology and Postdoc in Statistical Methods

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I am looking to fill two positions at the  Big Data Institute ,  Nuffield Department of Population Health ,  University of Oxford : a Data S...

Presentation: Genome-wide association studies of COVID-19

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An updated version of this talk given at the Nuffield Department for Population Health's annual symposium 2021:
Monday, 7 September 2020

Postdoc position available in Statistical Genomics

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I am seeking someone with a track record in methods development for Statistical Genomics and an interest in Infectious Disease to join the g...
Friday, 21 August 2020

Presentation: Genome-wide Association Studies of COVID-19

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An online recording of the talk about Genome-wide Association Studies of COVID-19 at the UK Biobank 2020 meeting on 23 June 2020. The full c...

The group's research response to COVID-19

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This is an update on the group's research response to the COVID-19 pandemic. As an infectious disease group we have been keen to contrib...

Teaching: Online lectures and practical on Phylogenetics in Practice

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On March 16th, we were in the interesting position of running an infectious disease course at the Big Data Institute on the day the national...

Presentation on identifying COVID-19 inpatients from Public Health England data

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This is a presentation I gave at the COVID-19 Host Genetics Initiative meeting on 2nd July 2020 about using Public Health England's Se...
Monday, 20 July 2020

Royal Society Summer Science Exhibition 2020

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This year the Royal Society's Summer Science Exhibition was online , and included highlights and updates from previous exhibitors, among...
Friday, 20 March 2020

New paper: GenomegaMap for dN/dS in over 10,000 genomes

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Published this week in Molecular Biology and Evolution , is a new paper joint with the CRyPTIC Consortium "GenomegaMap: within-species...
Monday, 16 March 2020

Postdoc Available in Statistical Genetics

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The closing date for applications for this post is  noon on Wednesday 15th April 2020 . We are seeking an exceptional researcher with a tr...
Tuesday, 22 October 2019

Correction published and R package on GitHub

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The correction to "The harmonic mean p-value for combining dependent tests" has been published  www.pnas.org/content/early/2019/10...
Monday, 19 August 2019

Updated correction: The harmonic mean p-value for combining dependent tests

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—  To view a PDF version of this announcement  click here   — Important: Please update to version 3.0 of the harmonicmeanp R package...
Saturday, 6 July 2019

Correction: The harmonic mean p-value for combining dependent tests

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Important: this announcement has been superceded. Please see updated correction .  I would like to issue the following correction to ...
Monday, 25 February 2019

New paper: PVL toxin associated with pyomyositis

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In a new collaborative study published this week in eLife , we report a strong association between Staphylococcus aureus  that carry the P...
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Daniel Wilson
University of Oxford
Professor of Infectious Disease Genomics and educator in Data Science at the University of Oxford.
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