Daniel Wilson's Blog

Research in Population Genomics

Saturday, 6 July 2019

Correction: The harmonic mean p-value for combining dependent tests

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Important: this announcement has been superceded. Please see updated correction .  I would like to issue the following correction to ...
Monday, 25 February 2019

New paper: PVL toxin associated with pyomyositis

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In a new collaborative study published this week in eLife , we report a strong association between Staphylococcus aureus  that carry the P...
Monday, 7 January 2019

New paper in PNAS: harmonic mean p-value

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Published on Friday in Proceedings of the National Academy of Sciences USA , "The harmonic mean p -value for combining dependent tests...
Wednesday, 18 July 2018

Bacterial Doubling Times in the Wild

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How fast do bacteria grow outside the laboratory? This simple question is very difficult to address directly, because it is near-impossible ...
Friday, 29 June 2018

PhD Studentship: Genomic prediction of antimicrobial resistance spread

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This position is now closed An opportunity has arisen for a D.Phil.  ( Ph.D. ) place on the BBSRC -funded Oxford Interdisciplinary Bioscien...
Wednesday, 27 June 2018

Royal Society Summer Science Exhibition Stall July 2-8

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Next week researchers from the Modernising Medical Microbiology consortium, collaborating groups and I will exhibit the Resistance is Futile...
Friday, 18 May 2018

Postdoc positions in Data Science and Molecular Microbiology

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These positions are now closed As part of the move to the Big Data Institute , two new postdoctoral positions funded by the Robertson Found...

The group has moved to the Big Data Institute, University of Oxford

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From April we have moved to the Big Data Institute , Nuffield Department of Population Health at the University of Oxford . The group is ...
Sunday, 31 December 2017

New paper: Severe infections emerge from commensal bacteria by adaptive evolution

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Published this month in eLife , our new paper on the evolution and adaptation of Staphylococcus aureus during infection. This study sho...
Monday, 18 December 2017

SCOTTI wins PLoS Computational Biology Research Prize

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Work from our group has been recognised in the PLoS Computational Biology 2017 Research Prizes. SCOTTI , which infers transmission routes f...
Monday, 11 September 2017

Promiscuous bacteria have staying power

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An insight article with Ruth Massey on John Lees' and Stephen Bentley's new paper was published in eLife on Friday: Streptococcus...
Thursday, 3 August 2017

New draft paper on combining p-values through the harmonic mean

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In a preprint released today on Biorxiv I report a new method for improving the sensitivity to detect statistical signals by averaging over...
Thursday, 29 September 2016

New paper: SCOTTI Efficient reconstruction of transmission within outbreaks with the structured coalescent

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New paper published today in PLoS Computational Biology : Understanding how infectious disease spreads and where it originates is essentia...
Friday, 23 September 2016

Prize PhD Studentships available

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I am offering two PhD projects as part of the annual Nuffield Department of Medicine Prize Studentship competition: Real-time detection of...
Friday, 19 August 2016

The Rsp virulence regulator: new review in Trends in Microbiology

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In the September issue of Trends in Microbiology , Mark Smeltzer casts the spotlight on the story of rsp , a virulence regulator in Staphyl...
Wednesday, 3 August 2016

Lyre bird song

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Healesville Sanctuary , Yarra Valley, Victoria, Australia
Thursday, 30 June 2016

Tackling and tracking TB through DNA analysis

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Friday, 17 June 2016

Collaborative PhD and postdoc positions available

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Dr Nicole Stoesser, Prof. Derrick Crook, myself and colleagues in Oxford are seeking a postdoc in Microbial Genomics with statistics skills ...
Tuesday, 17 May 2016

New paper: How low-toxic Staph. aureus mutants cause severe infections

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Published today in PNAS Early Edition , our new paper that reveals naturally occurring mutations in the poorly-described rsp gene of Stap...
Tuesday, 12 April 2016

Postdoctoral Scientist in Statistical Genomics

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We are recruiting for a Postdoctoral Scientist in Statistical Genomics working on Antimicrobial Resistance ( AMR ) gene discovery and focu...
Thursday, 7 April 2016

Making the most of bacterial GWAS: new paper in Nature Microbiology

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In a new paper published this week in Nature Microbiology , we report the performance of genome wide association studies (GWAS) in bacteria ...
Wednesday, 30 March 2016

CRyPTIC: rapid diagnosis of drug resistance in TB

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The Modernising Medical Microbiology consortium has announced a new worldwide collaboration called CRyPTIC to speed up diagnosis of antibio...
Saturday, 5 March 2016

Snow Monkeys in Japan

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Recently got back from the SMBE Satellite meeting on Pathogen Genomics in Japan. The organizers did a fantastic job and the talks were grea...
1 comment:
Wednesday, 20 January 2016

Nature Reviews Microbiology: Within-host evolution of bacterial pathogens

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Our new review of what genomics has taught us about Within-host evolution of bacterial pathogens has been published in Nature Reviews Micro...
1 comment:
Friday, 9 October 2015

PLoS Biology: Staphylococcus aureus invading the blood are less toxic

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Toxicity in nose, blood and skin bacteria . Collaborative work with Ruth Massey's group at the University of Bath taking forward a ...
2 comments:
Tuesday, 8 September 2015

New paper: Rapid host switching in Campylobacter

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Our new open access paper Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections was publi...
2 comments:
Monday, 17 August 2015

BASTA: Improved method for phylogeography

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This week sees publication of our paper New Routes to Phylogeography: a Bayesian Structured Coalescent Approximation in PLoS Genetics . P...
Friday, 24 July 2015

New Journal: Microbial Genomics

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This week sees the launch of Microbial Genomics , a new open access journal from the Society for General Microbiology . Here's an ex...
1 comment:
Tuesday, 21 July 2015

Resistance is Futile: Science Museum Lates and Cheltenham Science Festival

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Some photos from this summer's Science Museum Lates event with the Royal Society and the Cheltenham Science Festival . Thanks to every...
Wednesday, 8 April 2015

World Health Day: Food-borne disease theme

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For World Health Day 2015, the group's research into food-borne campylobacter infection was featured on the Nuffield Department of Medi...
1 comment:
Tuesday, 31 March 2015

ClonalFrameML: accounting for recombination in bacterial phylogenies

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Horizontal gene transfer in bacteria, mediated by transformation, transduction or conjugation, can result in gain, loss and replacement of...
2 comments:
Friday, 28 November 2014

New paper: bacterial phylogenetic inference is robust to recombination but demographic inference is not

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Published this week in mBio , Jessica Hedge's new paper " Bacterial phylogenetic inference is robust to recombination but demograph...
1 comment:
Friday, 6 June 2014

Cheltenham Science Festival

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Earlier this week members of the group represented the Nuffield Department of Medicine at the Cheltenham Science Festival with our Mod...
3 comments:

New paper: Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus

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This week published in Nature Communications we have a new open access paper looking at what drives variability in rates of recombination...
Tuesday, 1 October 2013

The role of hospital transmission in Clostridium difficile infection

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This week the Modernising Medical Microbiology consortium at Oxford published the findings of a six-year study into the transmission of the...
1 comment:
Friday, 20 September 2013

Postdoctoral Position in Statistical Genomics

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The position of Postdoctoral Scientist is available in my group to lead research on the Wellcome Trust and Royal Society funded project Sta...
3 comments:
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Daniel Wilson
University of Oxford
Professor of Infectious Disease Genomics and educator in Data Science at the University of Oxford.
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